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What are Autoimmune Diseases and How Do They Develop?

What are Autoimmune Diseases? Autoimmune Diseases are caused when the immune system attacks its own cells. This video is about autoimmunity, how autoimmune diseases develop, and the symptoms they cause. Find out how autoimmune antibodies, B-cells and T-cells get made and how they get activated. Autoimmune cells are activated via molecular mimicry, bystander activation and epitope spreading. Persistent infections can increase the stimulation of the immune system over a person's lifetime and increase the chances of activating autoimmune cells. Autoimmune Diseases can affect one organ, as in Type I Diabetes or many organs, as in Lupus. More than 100 autoimmune disorders affect 5-10% of people worldwide. 🌏 https://www.clevalab.com 📖 This video is also a blog post with images, references and as a PDF Summary, visit: https://www.clevalab.com/post/what-ar... 👉 You may also like: Growing Organs    • Growing Organs | Stem cells, Organoid...   Visit the ClevaLab Channel Page for more videos:    / @clevalab   ✉️ Sign up to the email list to be notified of new videos: https://www.clevalab.com/email-subscr... SOCIAL MEDIA LINKS Twitter:   / _clevalab   Instagram:   / _clevalab   Pinterest: https://www.pinterest.com.au/ClevaLab Tiktok:   / clevalab   Facebook:   / clevalab   CHAPTERS: 00:00 What is an Autoimmune Disease? 00:13 Types of Autoimmune Disease 00:38 Autoimmune Disease Risk 00:59 Autoimmune Disease Symptoms 01:15 Autoimmune Disease Diagnosis 01:27 Autoantibodies 01:53 Autoimmunity and Immune Tolerance 02:27 Role of Antibodies 02:33 B-Cell Development 03:14 T-cell Development 04:04 Activation of Autoreactive B & T-Cells 04:10 Molecular Mimicry 04:35 Bystander Activation 05:11 Epitope Spread 06:40 Viral Persistence 06:59 Symptoms Depend on Target Antigen 07:79 Autoimmune Disease Treatment #ClevaLab #autoimmunedisease #autoimmunediseases