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5. Coenzyme, Cofactor and Prosthetic group

small nonprotein molecules and metal ions directly participate in substrate binding or catalysis known as coenzymes, cofactors or prosthetic groups Coenzyme- Nonprotein, organic, LMW, dialysable substance associated with enzyme action Cofactor- metal ions bound loosely with enzymes Prosthetic groups- tight and stable association with enzyme. classified in the basis of 1. precursor molecule 2. group transfer