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How Toxoplasma Switches Between its Fast and Slow-Growing Forms

Toxoplasma gondii causes a disease called toxoplasmosis, which can be spread to humans from infected cats. It's one of the most common human parasites. It has been a challenge for scientists to figure out how it switches from its fast-growing state that causes life-threatening infections to its chronic, slow-growing form — a process called differentiation. Now, Whitehead Institute researchers have identified a master regulator of differentiation — a gene called BFD1 that orchestrates the shift in life cycle. The discovery provides a new target for treating and preventing Toxoplasma infections. Learn more about the new study at wi.mit.edu. Music: A.A. Aalto (CC-BY-NC)