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How to Sequence a Human Genome in 7 'Easy' Steps! 1 год назад


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How to Sequence a Human Genome in 7 'Easy' Steps!

Join NHGRI researchers at the NIH Intramural Sequencing Center (NISC) as they show you step-by-step how to extract human DNA, sequence it, and interpret the data -- with some fun DNA high jinks along the way. Step 1: Find a DNA sample.  Step 2: Isolate the cells by centrifugation.  Step 3: Extract the DNA from the sample. Step 4: Load the sample into the sequencer. Step 5: Wait for the data to be generated. Step 6: Use the data you have collected to build the genome. Step 7: Analyze the DNA sequence data for quality. Done! High five your team! #t2t Learn more about how scientists completed the first complete, gapless sequence of a human genome: https://www.genome.gov/T2T More about The NIH Intramural Sequencing Center (NISC) https://www.nisc.nih.gov/ *Note: Methods have been oversimplified for communications purposes. Sequencing a full human genome is actually quite challenging!* Credits: Producer/Writer/Director: Jenny Montooth, M.A., NHGRI Videographer/Animator/Editor: Ernesto Del Aguila III, NHGRI Cameraperson: Darryl Leja, M.A., NHGRI Audio: Alvaro Encinas, NHGRI Executive Producer: Sarah Bates, M.A., M.S., NHGRI Starring: Adam Phillippy, Ph.D., NHGRI Shelise Brooks, NISC Sergey Koren, Ph.D., NHGRI Arang Rhie, Ph.D., NHGRI Brandon Pickett, Ph.D., NHGRI

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