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Monoclonal B-cell lymphocytosis: at a crossroad between disease and senescence

Monoclonal B-cell lymphocytosis (MBL) is a preleukemic condition that can evolve into chronic lymphocytic leukemia (CLL). In this video, Paolo Ghia, MD, Vita-Salute San Raffaele University, Milan, Italy, explains why widespread population screening for MBL is not needed, as most patients with low-count MBL do not go on to develop CLL. The presence of high-count MBL represents a 1-2% increased annual risk of developing CLL, so regular surveillance is necessary in individuals where high-count MBL is detected. This interview took place at the 65th ASH Annual Meeting and Exposition, held in San Diego, CA. These works are owned by Magdalen Medical Publishing (MMP) and are protected by copyright laws and treaties around the world. All rights are reserved.