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USMLE Inflammation & Immunology High Yield Rating List

USMLE Step 1 High Yield Ratings List for Inflammation & Immunology: 10 – B & T Cell Activation 9 – Toxoid Vaccines 9 – Antibody Isotypes 8 – Type I Hypersensitivity 7 – Tumor Necrosis Factor 7 – Interferon 7 - Chronic Granulomatous Disease (CGD) 6 – Prostaglandins, Leukotrienes & Bradykinin 6 – Chronic Organ Transplant Rejection 5 – Type IV Hypersensitivity 5 – Type III Hypersensitivity 5 – Scar Formation 5 – Interleukin 2 5 – DiGeorge Syndrome 4 – Live/Attenuated Vaccines 4 – Graft vs. Host 4 – Complement System 4 – Cardinal Signs of Inflammation 4 – Autoantibodies 3 - X-Linked Agammaglobinemia 3 – Transudate vs. Exudate 3 - Severe Combined Immunodeficiency 3 – Neutrophil Extravasation 3 – Killed/Inactivated Vaccines 3 – Interleukin 1 3 – Granulomas 2 – MPO Deficiency 2 – IgA Deficiency 2 – Chemotactic Factors IL-8 & LTB4 2 – Acute Organ Transplant Rejection 1 – Type II Hypersensitivity 1 – Passive vs. Active Immunization 1 – Hyperacute Organ Transplant Rejection 1 – B & T Cell Development 1 – Antibody Structure No Yield: Wiskott-Aldrich Congenital Neutropenia Leukocyte Adhesion Deficiency Common Variable Immunodeficiency Hyper IgE IL-12 Receptor Deficiency Ataxia Telangiectasia IL – 3,4, 5, 6, 10, 12 HLA Subtypes Tacrolimus Most recombinant cytokines Adalimumab Rituximab Omalizumab