Скачать с ютуб Pseudohypoparathyroidism : Part 1 : Pathology в хорошем качестве

Pseudohypoparathyroidism : Part 1 : Pathology

𝐒𝐮𝐛𝐬𝐜𝐫𝐢𝐛𝐞 𝗙𝐨𝐫 𝗠𝐨𝐫𝐞 𝗜𝐧𝐟𝐨𝐫𝐦𝐚𝐭𝐢𝐨𝐧 𝐨𝐧 𝗛𝐞𝐚𝐥𝐭𝐡 👩‍⚕‍ 𝐚𝐧𝐝 𝗠𝐞𝐝𝐢𝐜𝐢𝐧𝐞💉🩺💊 𝐘𝐨𝐮𝐭𝐮𝐛𝐞 :    / @medschoolsimplified007   📌𝗙𝗮𝗰𝗲𝗯𝗼𝗼𝗸 :   / draishwaryakelkar   📌𝗧𝘄𝗶𝘁𝘁𝗲𝗿:   / aishwayadr   📌𝗜𝗻𝘀𝘁𝗮𝗴𝗿𝗮𝗺 :   / clinical.learning   Pseudohypoparathyroidism : Part 1 : Pathology ---------------------------------------------------------------------------- Pseudohypoparathyroidism is a rare endocrine disorder characterized by resistance to parathyroid hormone (PTH), leading to hypocalcemia and hyperphosphatemia despite elevated levels of PTH. This condition is caused by mutations in the GNAS gene, which encodes the G protein alpha subunit involved in PTH signaling. The disruption in this signaling pathway prevents PTH from exerting its effects on target tissues, such as the kidneys and bones, resulting in impaired calcium and phosphate metabolism. Clinically, patients may present with features of Albright's hereditary osteodystrophy, including short stature, obesity, brachydactyly, and subcutaneous calcifications. The diagnosis is confirmed through biochemical tests showing low calcium and high phosphate levels alongside elevated PTH, and genetic testing for GNAS mutations. Understanding the pathophysiology of pseudohypoparathyroidism is crucial for proper diagnosis and management, focusing on addressing the metabolic imbalances and associated clinical manifestations. #Pseudohypoparathyroidism #Endocrinology #Pathology #FMGE #NEETPG #USMLE #MedicalStudents #Hypocalcemia #Hyperphosphatemia #GNASGene #MedEd #StudyMedicine #HealthScience #MedicalExams #FutureDoctors #EndocrineDisorders #CalciumMetabolism #LearnMedicine #ParathyroidHormone #GeneticDisorders