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How proteins C and S inhibit clotting factors 5 and 8 (FV and FVIII) to stop blood coagulation...Bleeding disorders. 😍🖼Animated Mnemonics (Picmonic): https://www.picmonic.com/viphookup/me... - With Picmonic, get your life back by studying less and remembering more. Medical and Nursing students say that Picmonic is the most comprehensive and effective way to bridge learning and test prep... Disclaimer: I use affiliate links.... ►👨🏫💊Antibiotics Lectures: https://www.medicosisperfectionalis.c... ... Check out my brand new "Electrolytes" course at https://www.medicosisperfectionalis.c... and use the PROMO code: ELECTROLYTES50 to get a 50% discount. 😅 If you like mnemonics, try Picmonic: https://www.picmonic.com/referrals/JK... Protein C and protein S are vitamin K-dependent factors that inhibit blood coagulation (2ry hemostasis) by inhibiting the active factors 5 and 8 (Va and VIIIa). They are produced in the liver via gamma carboxylation (vitamin K dependent). We have discussed thrombomodulin in a previous video in this playlist, titled "bleeding and coagulation". You can get all of my notes and cases at / medicosis Factor V Leiden is a genetic disorder where the factor V is mutant and therefore resistant to inactivation by the activated protein C (APC) leading to excessive thromboses (i.e. hypercoagulability). If you like my videos, please consider leaving a tip at https://www.paypal.me/perfectionalis/ ► Visit my website: https://www.medicosisperfectionalis.com/ My Favorite Productivity App: https://airtable.com/invite/r/2zH40fus/ 📱Save on your mobile phone bill: http://fbuy.me/q6bMj 🏦 Qbank (TrueLearn): https://truelearn.referralrock.com/l/...