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MORPHOLOGY OF CELL INJURY: REVERSIBLE & IRREVERSIBLE. Necrosis & its types.

A series of video tutorials discussing the pathology of cell injury and adaptations. In this tutorial , i have discussed Morphology of Reversible and Reversible cell injury ***Follow me**** http://ilovepathology.com/ Twitter :   / vijaypatho     / ilovepathology2   Facebook:   / ilovepathology   Morphology of reversible cell injury : hydropic change Morphology of irreversible cell injury : Autolysis, Necrosis, types & examples Autolysis • “self digestion” • Disintegration of the cell by its own hydrolytic enzymes liberated from lysosomes • Rate of autolysis depends on the hydrolytic enzymes • Morphology – homogenous and eosinophilic cytoplasm with loss of cellular details Necrosis • Localised area of cell death followed by degradation of the tissue by the hydrolytic enzymes • ALWAYS accompanied by inflammatory reaction Mechanisms 1. Denaturation of the intracellular proteins 2. Enzymatic digestion of the cell Types of necrosis • Mass of necrosis has several morphological patterns • Coagulative • Liquefaction • Caseous • Fat & • Fibrinoid ~-~~-~~~-~~-~ Please watch: "WARBURG EFFECT: Hallmark of CANCER. What, Why & How?"    • NEOPLASIA 6: WARBURG EFFECT: Hallmark...   ~-~~-~~~-~~-~