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Soft tissue Sarcoma cancer | A diagnostic and treatment overview |

Soft tissue sarcoma can occur anywhere in your body, but the most common types occur in the arms and legs, and in the abdomen. Surgical removal is the most common treatment, although radiation and chemotherapy also may be recommended — depending on the size, type, location and aggressiveness of the tumor. Types Angiosarcoma Dermatofibrosarcoma protuberans Epithelioid sarcoma Gastrointestinal stromal tumor (GIST) Kaposi's sarcoma Leiomyosarcoma Liposarcoma Malignant peripheral nerve sheath tumors Myxofibrosarcoma Rhabdomyosarcoma Solitary fibrous tumor Synovial sarcoma Undifferentiated pleomorphic sarcoma Symptoms A soft tissue sarcoma may not cause any signs and symptoms in its early stages. As the tumor grows, it may cause: A noticeable lump or swelling Pain, if a tumor presses on nerves or muscles When to see a doctor Make an appointment with your doctor if you have: A lump that is increasing in size or becomes painful A lump of any size that's located deep within a muscle Recurrence of a lump that's been removed Causes In most cases, it's not clear what causes soft tissue sarcoma. In general, cancer occurs when cells develop errors (mutations) in their DNA. The errors make cells grow and divide out of control. The accumulating abnormal cells form a tumor that can grow to invade nearby structures and the abnormal cells can spread to other parts of the body. The type of cell that develops the genetic mutation determines what type of soft tissue sarcoma you have. For example, angiosarcoma begins in the lining of blood vessels, while liposarcoma arises from fat cells. Some types of soft tissue sarcoma include: Angiosarcoma Dermatofibrosarcoma protuberans Epithelioid sarcoma Gastrointestinal stromal tumor (GIST) Kaposi's sarcoma Leiomyosarcoma Liposarcoma Malignant peripheral nerve sheath tumor Myxofibrosarcoma Rhabdomyosarcoma Solitary fibrous tumor Synovial sarcoma Undifferentiated (pleomorphic sarcoma) Risk factors Factors that may increase your risk of sarcoma include: Inherited syndromes. A risk of soft tissue sarcoma can be inherited from your parents. Genetic syndromes that increase your risk include hereditary retinoblastoma, Li-Fraumeni syndrome, familial adenomatous polyposis, neurofibromatosis, tuberous sclerosis and Werner syndrome. Chemical exposure. Being exposed to certain chemicals, such as herbicides, arsenic and dioxin, may increase the risk of soft tissue sarcomas. Radiation exposure. Previous radiation treatment for other cancers can increase the risk of soft tissue sarcomas. #soft #tissue #sarcoma #cancer #explanation #video #biology #medical #video