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Treatments in Autoimmune Encephalitis

Dr. Bruce Cree, Associate Professor of neurology at the UCSF School of Medicine, gives an outstanding presentation on Autoimmune Encephalitis and the treatments used in this rare group of diseases. A notable component of the treatments in Autoimmune Encephalitis are the clinical trials currently available that will lead to FDA-approved treatments for future patients. Patients who are recently diagnosed and their clinicians should discuss the value of participating in these trials. Autoimmune Encephalitis is a group of inflammatory brain diseases that are characterized by prominent neuropsychiatric symptoms. These patients are often believed to have psychiatric presentations, but they do NOT. Common clinical features include a change in behavior, psychosis, seizures, memory and cognitive deficits, abnormal movements, dysautonomia, and a decreased level of consciousness. Psychiatrists and Emergency Room Physicians are often the first medical professionals who see these patients. It is vital that Clinicians consider the possibility of an autoantibody-related etiology and become familiar with the red flags suggestive of synaptic autoimmunity as the underlying cause in all cases of first-onset, out-of-the-blue psychosis. A high level of suspicion is necessary as autoimmune encephalitis is treatable with immunotherapy. Firm evidence shows that earlier recognition and treatment lead to improved outcomes. It is important to note, that the disorder is refractory to antipsychotics; indeed, antipsychotic agents make affected patients much worse, even to the point of developing something akin to the neuroleptic malignant syndrome. The International Autoimmune Encephalitis Society, (IAES), is the only Family/Patient-centered organization for people with a diagnosis of Autoimmune Encephalitis. Leading with integrity, IAES strives to advance services, education, increased awareness, and research for this group of diseases. IAES provides science-based information backed by trusted medical experts in the field of autoimmune neurology and relies on the expertise of our Medical Advisory Board. We are an established non-profit organization with a history of supporting all-inclusive services from diagnosis to recovery and the many challenges experienced in that journey. Visit our website: www.autoimmune-encephalitis.org Your donations help us continue our important work. https://autoimmune-encephalitis.org/d...