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Phospholipase C - IP3, DAG Pathway || Gq protein pathway

Find notes here: https://www.nonstopneuron.com/post/ph... Explore our entire animation video library at: https://www.nonstopneuron.com/ Video Summary: Binding of a ligand with Gq protein-coupled receptor causes release of GDP and binding of GTP. The α subunit then dissociates and activates phospholipase C. Phospholipase C degrades PIP2 into IP3 and DAG. IP3 goes to the endoplasmic reticulum and opens the Ca channel. Released Ca binds with calmodulin. Ca-CaM complex alters the activity of downstream enzymes for example MLCK. DAG activates PKC which modulates the activity of other proteins like MARCKS proteins and transcription factors. 🎞 More videos on Signaling: • G Protein Coupled Receptors:    • G Protein Coupled Receptors (GPCR) & ...   • Adenylyl Cyclase - cAMP Pathway:    • Adenylyl Cyclase - cAMP Pathway || Gs...   • Cell to Cell Communication:    • Cell to Cell Communication || Types o...   • Receptor - Types & Functions:    • Receptors: Types & Functions   • Intracellular Signaling / Second Messenger System:    • Intracellular Signaling / Second Mess...   • Receptor Tyrosine Kinase:    • Receptor Tyrosine Kinase || MAPK Pathway   ● Follow me at: • Facebook:   / nonstopneuron   • Instagram:   / nonstopneuron   Dr Vipul Navadiya DISCLAIMER: This video is for education purposes only. Although every effort is made to ensure the accuracy of the material, viewers should refer to the appropriate regulatory body/authorized websites, guidelines, and other suitable sources of information as deemed relevant and applicable. In view of the possibility of human error or changes in medical science, any person or organization involved in the preparation of this work accepts no responsibility for any errors or omissions, or results obtained from the use of information in this video.