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The ASPro PD phase 3 clinical trial of Ambroxol by Cure Parkinson's.An update and panel discussion

This is the recording of Professor Anthony Schapira’s presentation on 23rd February 2023 at the Royal School of Medicine London supported by Cure Parkinson's After reviewing pre-clinical laboratory data from Professor Anthony Schapira’s team at UCL, a committee of experts brought together by Cure Parkinson’s, prioritised the simple cough medicine ambroxol for further investigation; agreeing that it has the potential to slow the progression of Parkinson’s. This decision was based on the demonstration that ambroxol could improve the breakdown and clearance of waste proteins that build-up and clump together in brain cells – a characteristic feature of Parkinson’s. The UK-based phase 2 clinical trial of ambroxol in 17 people with Parkinson’s, was funded and supported by Cure Parkinson’s, Van Andel Institute and the John Black Charitable Foundation; and the results of that study, together with additional pre-clinical and clinical findings, support ambroxol and other drugs in this class of so-called GCase-modulators as a promising area of research to slow or stop the progression of Parkinson’s. Now, the phase 3 trial of ambroxol called ‘ASPro – PD’ will begin, funded by Cure Parkinson’s alongside its strategic partners Van Andel Institute and the John Black Charitable Foundation, and by the Parkinson’s Virtual Biotech, the drug discovery and development arm of Parkinson’s UK. The trial, it is hoped, will determine if ambroxol can slow the progression of Parkinson’s. Learn more here:- https://cureparkinsons.org.uk/ambroxo... Learn more about Prof Anthony Schapira here:- https://www.ucl.ac.uk/ion/people/anth...    • Parkinson disease - Prof. Tony Schapi...   DONATE TO CURE PARKINSON'S:- https://cureparkinsons.org.uk/donate-... More about The Van Andel Institute can be found here:- https://www.vai.org/ https://www.vai.org/article/van-andel... IF YOU CAN, PLEASE DONATE TO NO SILVER BULLET 4PD. We are self-funded, so pay for our costs ourselves, which include licenses for our secure Webinar platform, our Podcast hosting platform and soon-to-be-launched paid advertising on Facebook and Instagram so that we can target and share these sessions with more PwP worldwide, in the hope that some of our speaker's content, may improve the symptoms of another PwP Thank you & just follow this link:- https://www.paypal.com/donate/?hosted...